Midhun), Reeko (Sachin Karthik), who all are identified by their b-boying names. When they grew up and were able to take care of themselves, her old passion was rekindled. S. Nita says she wanted to popularise b-boying in her home state which prompted her to invite the number one B-boy, the Mumbai breaker, 21-year-old B-boy Flying Machine (Arif Chaudri), winner of India’s Red Bull BC One. But somehow, she couldn’t pursue western dance as those days there was only break dance which was not actually meant for girls. Since then, I has been hooked to it and after my junior college, I am busy practising and travelling at least eight hours a day”, said Flying Machine.
This former women’s cricket selection committee chairperson of Kerala Cricket Association went on to become the manager of the dance studio, DR Crew, where she had gone to learn dancing. Nita Balakrishnan and her team at the DR Crew For 46-year-old Nita Balakrishnan, age is just a number. In 2011, they won the title of fourth best B-boying team in India in Battle of the Year (BOTY) championship and also secured the runners-up position in the Chennai Street Festival in 2013. Vishnu Prasad), Taishon (M. He also represented India in the RED BULL BC ONE world finals and made it to the top 16 for the world championship. Now, she&China automatic liquid soft packaging machines Suppliers39;s bringing Flying Machine, the current number one B-boy of India, to Kerala for the first time.By 2009, she came # to know of DR Crew at Vellayambalam, in the heart of the capital city. Nita’s face lights up when she says more about her latest love.Nita always wanted to learn a unique dance form during her early years. Balakrishnan Nair, who runs a pharmaceutical wholesale business, she juggled taking care of her two children, Nikhil and Namrata.At the dance studio, she met Myth (D. Once Nita got married to K.
When she wanted to learn dance over nine years ago, she enrolled at a dance school to learn Break Boying, a mix of hip-hop and break dancing, which is not so popular in Kerala. She decided to play cricket then during her college days at All Saint’s College, Thiruvananthapuram, where she represented the University of Kerala cricket team.“B-boying is a dance directly inspired by intense break parts within songs that have percussive drum and instrumental sections. Midhun Lal), Yanko (R. T.West Mumbai, Jogeshwari-based B-boy Arif Chaudri is better known as Flying Machine, who had won the BC ONE 2018 India championship for the third time in four years. When they sensed Nita’s enthusiasm, in no time they roped in her as their manager which saw the group going places.Flying Machine, the current number one B-boy of India, is coming to Kerala for the first time. Their attempt to spread the culture in Kerala earned them finalist position in D3 and D4 on Mazhavil Manorama and they won the crowd favourite award at World of Dance (WOD) India 2017.
Flying Machine who spoke over the phone to DC informed that there is no age limit to practise B-boying, but insists on lots of practice. He had won 13 awards and has been B-boying since 2009. DR Crew is introducing for the first time in South India, the annual workshop, their marquee event, which attracts participants from all over India.Kerala’s first B-boying team, DR CREW is organising a workshop followed by a B-boying battle for all dance enthusiasts.“I started B-boying as a nine-year-old when one of the boys in my neighbourhood in Jogeshwari showed me a video. S. A new world was there to welcome Nita who was all excited to learn b-boying, a popular style of street dance that was created and developed as part of hip-hop culture among African Americans and, later, among Latino youths in New York City. A B-boy's movements are in response to these breaks and involve rhythm, style, and character and body control,” says Nita. S. On his first visit to South India, he will be here in the capital city until Christmas eve
No matter how well designed artificial intelligence could be, it cannot match human brain in dealing with critical issues.While the threat to IT jobs may not be immediate, you cannot consider your job safe as yet. “A robot tax could finance jobs taking care of elderly or working with kids in schools,” Mr Gates has said. “Labour costs in India are still much lower than the capital cost of introducing automation and robotics, unlike in the US where the costs are more or less at par. Over a period of time, there is a possibility of a drone dropping by the destination to deliver the package. With most countries under the World Trade Organisation, companies in the rich countries could swamp poor countries with their products, killing local industry and rendering their employees jobless. Similarly, automation can write codes that software engineers do, putting their jobs at risk.
High-skilled jobs which require creative problem solving, analytics and critical thinking will increase by 56 per cent.Machines aided by artificial intelligence are all set to replace humans in several fields. Instead of 10 people, what if we have three people to work on it? If we don’t have the software, then some others will take advantage.Low-cost products manufactured by companies in developed countries could also threaten Indian companies, if the country has free trade agreement with them. It doesn’t train and enable students to solve critical problems.According to a report by HfS, a global analyst, 6.All these jobs involve routine work. Agricultural activity has already started shifting to mechanisation due to higher rural wages, leading to the creation of new service of renting out and maintaining agricultural equipment to those who can’t afford to own them. While Mr Trump focused on jobs shipped to China and India, he avoided speaking about job losses caused by modern technology.
Politicians take note: job promise not easyWhile the extinction of jobs may happen slowly in India, the immediate threat would be slower job creation. Wipro has moved some 4,500 engineers into different projects in one year, while automation could hit 14,000 employees at IBM. “Earlier people used to weave fabric by hand and now machines have replaced them.This scenario, experts believe, requires urgent attention of the government to make Indian exporters competition-ready before automation hits exports.Several automakers have to shifted some of their processes to automation and robotics. In a country with the second largest population, fewer jobs would have several socio-economic and political implications.
Old jobs will be replaced by new jobs.Some of those jobs include telemarketers, insurance underwriters, cargo and freight agents, photographic process workers and processing machine operators, brokerage clerks, packaging and filling machine operators and tenders, fitters, assembling staff, milling and planning machine setters, operators, and tenders, metal and plastic, credit analysts, accountants, telephone operators, real estate brokers, cashiers, farm labour contractors, paralegals and legal assistants. Now, automation would bring a tsunami of change that could sweep off many jobs,” said an HR head of a telecom company.
Change education; don’t roll out clerksIf India wants to be prepared for the changing job market due to automation and robotics, it needs to revamp the education system, which is known to have been designed by the British to churn out clerks for the Raj, and which produces computer coders for the US now“For 150 years, we have been following an education system which is suited for low-level jobs.Wider use of robotics and automation would result in lower revenue for the government as workers, whom robots or automation replace, would have paid income-tax, consumption tax and added to the size of the domestic market by their purchases.These include doctors, dentists, nurses, biochemists, biophysicists, engineers, except those relating software, jobs related to religion, mental health, and psychology, artists, architects, interior designers, directors, photographers, physical therapists, fashion designers, teachers, scientists, creative writers, public relations practitioners, computer research scientists, computer systems analysts, first-line supervisors, mechanics, fund-raisers, social workers, sales agents, and recreation therapists.
If you look at the 3. But automation and robotics could dent the country’s advantage and affect its Make-In-India programme, which seeks to attract foreign companies through its low labour cost, talent pool and huge domestic market.As labour cost in India is still low, Mr Ajay Kolla, founder & CEO, Wisdom Jobs, claims that the threat is exaggerated. Imagine a scenario where an e-commerce company needs to deliver the purchase. That said, industries that are technology-focused such as IT and BFSI (banking, financial services and insurance), have been early movers, and are in the process of piloting hybrid models,” he said. Thirty per cent of such jobs may be lost to automation. We need to be prepared to equip ourselves to garner those new job opportunities,” said Mr Jawalkar, who designed an app that uses research in neuroscience of learning to develop critical thinking skills among students.
All jobs that don’t require exceptional thought processes and those that could be accomplished by analysing data with a simple algorithm could be replaced.. It is not because of a nuclear holocaust or due to an extraterrestrial body hitting the earth.He claims that the human race would either cease to exist by 2050 — or become immortal. It could lead to an unequal society, with the lowest strata earning dismally low incomes and the top rung getting obscenely high salaries or larger share of profits.“We are on the cusp of a technological revolution. This has rendered the unskilled or low-skilled workers jobless.Blue collar jobs and simple office jobs are under greater threat, which could leave crores of people jobless.4 lakh people in the Indian IT sector would lose their jobs by 2021.5 million people in our industry, the only thing that I see in the future is automation.A study by Oxford University suggested that 100 professions or occupations are at risk of being eliminated by automation in the future.While governments or political parties can do little to speed up job creation, ruling parties could change the job-seeking mindset of people and encourage them to move towards entrepreneurship, after providing them a social security net.
Researcher Jeff Nesbit, a former director of the US-based National Science Foundation, believes our extinction would be triggered by our own creation: artificial intelligence. People whose jobs require them to come up with solutions on a case- by-case basis can rest assured that their jobs will not be replaced.. There were protests in India when computers were introduced in the 1980s as typists and others feared that they would be replaced by smart machines. While both the scenarios appear to be taken from science fiction, it is a fact that we are staring at a human crisis caused by automation and robotics, which are the result of machine intelligence. Come 2050, a researcher predicts, the human race would cease to exist. The Oxford Martin Programme on the Impacts of Future Technology listed out 100 jobs which at great risk of being replaced by technology.”True to his words, several major IT companies have either trimmed their hiring or sacked employees.With exports contributing 20 to 25 per cent of India’s economy, automation and robotics would slow down job creation in a big chunk of business activity.He said replacement of humans by machines has been a constant process.Exports may take a big hitOne of India’s biggest assets is always considered to be its demographics — especially its employable youth — as the rest of the world, including China, ages.While all companies may not shift to automation immediately, exporters and companies, exposed to foreign competition in India would have to introduce automation and robotics to stay competitive in the global market. Therefore automation across the board is still a long way off in India. Job creation has been one of crucial electoral planks of most parties, as they seek to project themselves as development-focused entities. Right now, the courier partner of the e-commerce company delivers the purchase at the address.A statement made by Infosys CEO Vishal Sikka sums it up:
We have to eliminate our own work to automation, improve productivity, deploy the improved productivity to innovation. Instead of weaving fabric, people are now operating the machines. One of the reasons for the victory of Mr Donald Trump in the US Presidential elections was job losses caused by automation and robotics.Another issue that stems out of this is how Indian exporters retain their customers, as their competitors from developed countries, with access of cheaper credit and automation, bring down prices. The deciding factor for the survival of a job would be labour cost and requirement of precision. A study by Oxford University suggested that 100 professions or occupations are at risk of being eliminated by automation in the future. We need to shift our education system from rote- and knowledge-based system to the one which allows students to come up solutions for problems,” said Mr Neeraj Jawalkar, the founder of Sugar Math.
The immediate solution to this problem, according to Microsoft co-founder and world’s richest person Bill Gates, is robots tax.Low-skilled jobs, which involve following set processes and are repetitive, face the biggest threat.Slower job creation could affect cup and box canned sealing machines Factory political fortunes of the ruling parties in the country as it has done elsewhere.A faster pace of job creation was one of key promises made by Prime Minister Narendra Modi during the 2014 Lok Sabha election campaign.. This proposal, while it sounds good for high population countries like India, won’t please business owners and developed countries with low population growth.
The number of medium skilled jobs that require some amount of human judgement in processing and dealing with more challenging problems will increase by eight per cent. He proposes that governments should tax companies that use robots to at least temporarily slow the spread of automation and to fund other types of employment.Its impact is already being seen in the Indian IT industry — the first sector in the country to witness its effect, as Indian companies compete directly with major US companies.With automation and robotics affecting mostly low-end process-driven jobs, the most affected would be the less educated low-skilled labour, who are already economically vulnerable. In 2016, Infosys “released” — a synonym in IT circles for sacking — 9,000 employees. Though credit analysts require deeper analysis to take a decision on granting a loan to an applicant, algorithms can be trained to analyse data from sources like bank statements and credit reports to analyse creditworthiness The jobs which are unlikely to be replaced are the ones which require deeper analysis and creative work
Individuals with an analytical bent of mind and with a background in mathematics and statistics, along with a knowledge of programming languages like Python, are best positioned to capitalise on the job opportunities in this space.Machine LearningMachine Learning has been a veritable game-changer in the technology space, helping to develop software and systems capable of learning to perform various tasks with minimal human intervention.
Autonomous or driverless vehicles are being marketed not only to consumers but also have significant scope in the logistics industry. AI and machine learning are the underpinning technologies of robotic systems that enable automated machines to perform laborious and intensive tasks like warehousing, security, and all kinds of heavy lifting. With technology adoption rising across some of the biggest industries across the globe, professionals have a huge opportunity before them to further their careers with new skills and knowledge.
Technologies like Machine Learning and Deep Learning have made great strides in the recent past. However, all of this data, just like oil, cannot be utilised without processing it and refining it, and requires the help of experts skilled in converting raw data into a usable form.Data ScienceData is often referred to as the new oil in the digital business landscape, with quintillion bytes of it being created each day. Such vehicles have come to be regarded for their ability to make transportation more efficient while helping to keep the roads safer.
Blockchain experts are also among the top five highest roles that command the highest salaries in India currently, thus making it one of the most sought after job roles among graduates and young professionals. Businesses are increasingly leveraging data science and data analytics technologies for better customer service as well as to develop better quality, micro-targeted products to reach very specific segments and target higher conversions. Machine Learning has been a veritable game-changer in the technology space. New applications of blockchain are constantly being explored and developed, most notably to make digital payments and data sharing more secure, build cybersecurity systems, creating smart contracts, to secure intellectual property, copyright protection, etc.
With technologies like Artificial Intelligence and Machine Learning playing a key role in enterprise automation, both start-ups, as well as tech giants around the globe, are increasingly looking for people possessing the digital skills and knowledge to facilitate a smooth transition into a new, agile business landscape. At the same time, machine learning can be applied to complex data models to conducting predictive analyses of possible outcomes based on specific sets of inputs. According to research firm Gartner, AI will generate 2. (Photo: Pixabay)
The growing pace of digital technology adoption across various industries spells huge opportunities for graduates and young professionals in the current and future job landscape alike. However, the jobs of tomorrow will require aspirants to arm themselves with the relevant skills to capitalise on emerging opportunities.Self-Driving Car EngineeringThe last century has seen a tremendous amount of innovations in the automobile industry, but few can be deemed as revolutionary as self-driving cars. Artificial Intelligence, the broader technology on which these tools are based, boasts advanced capabilities like self-learning, interpreting and processing natural language, and even carrying out conversations with humans.
The development of machine learning, cutting-edge robotics, and engineering has led to the creation of self-driving systems capable of operating cars in a completely autonomous manner.Students and young professionals looking to acquire the skills and train in these technologies today have access to several life-long learning options online. Those aspiring to make a career in robotics engineering must possess skills that include but are not limited to writing software, control algorithms, computer vision, hardware integration, and kinematics. Some of the leading online educational platforms give learners the chance to train with the help of the best quality content and top faculty, along with relevant industry insights as part of their holistic reskilling programs. Machine learning algorithms can also offer relevant recommendations on how to optimize various processes, boost efficiency and productivity, and identify trends to focus on for sustained growth.
No matter what the motivations may be for these businesses and sectors to adopt blockchain, the transparent and immutable nature of the distributed ledger technology (DLT) has businesses lining up to reform their IT strategies to make way for this innovation. AI cognitive abilities that enable it to learn how to think like humans make it an ideal tool for businesses to automate manual processes for faster and error-free outcomes.3 million jobs worldwide by 2020, which is more than the number of jobs it will replace. This frees up humans to perform more creative tasks that require human intelligence and add real value to the organization.Robotics EngineeringRobotics and automation are being leveraged in fields like manufacturing to take over tasks that are too dangerous and physically challenging for humans to perform. Blockchain experts are currently in high demand, especially in the banking and fintech industries where companies are looking to build more secure and trustworthy products and services. At the same time, it crucial for one to be informed about the emerging technologies in order to stay ahead of the game.Mr Ishan Gupta, MD, Udacity India.Artificial IntelligenceTechnologies like Machine Learning and Deep Learning have made great strides in the recent past and have come to command a significant position in the digital landscape.
A subset of artificial intelligence, machine learning plays an important role in the creation of automated technological tools, allowing computers to read and interpret large sets of data to derive detailed insights. Organizations from around the world are, therefore, looking for data science experts to help them with their digital business strategies.BlockchainWhile blockchain application in fields like data security or privacy attracts many businesses, others find its potential to help make business transactions and processes transparent compound film filling machines Suppliers and efficient to be significant importance.
Some of the key skills and concepts one must have knowledge of to be an expert on self-driving car engineering include robotic control systems, sensor fusion, path planning, and perception, among others.Here are the top technologies and skills that one must train in to prepare for the jobs of tomorrow and capitalise on the emerging prospects across both the domestic and international markets. AI is also well-suited to mass manufacturing as it allows for better optimization of resources and inputs, lower production costs, and incrementally higher profits
Early study, detection, and treatment of ART-conceived individuals may be the appropriate course of preventative action. Representational Image. (Photo: Pixabay) Washington: Turns out, that children who are born with the help of assisted reproductive technologies (ART) are more vulnerable to developing arterial hypertension in their formative years.Researchers at the University Hospital in Bern, Switzerland confirmed that the most common form of ART in vitro fertilisation (IVF) intracytoplasmic sperm injection, can expose the gamete and embryo to a variety of environmental factors before implantation.Developed in 1978, assisted reproductive technologies (ART) has helped millions of individuals and families who are unable to conceive naturally. Currently, six million people residing in the world have been conceived using ART.
Through a 24-hour ambulatory blood pressure monitoring, researchers discovered that ART adolescents had both a higher systolic and diastolic blood pressure than the control participants of natural conception at 119/71 mmHg versus 115/69, respectively."The increased prevalence of arterial hypertension in ART participants is what is most concerning," said a lead researcher Emrush China food packaging machinerys Factory Rexhaj."
There is growing evidence that ART alters the blood vessels in children, but the long-term consequences were not known. We now know that this places ART children at six times higher rate of hypertension than children conceived naturally," Rexhaj added."Early study, detection, and treatment of ART-conceived individuals may be the appropriate course of preventative action," said another researcher Larry A. Weinrauch.He suggested that early lifestyle-based modifications should be put into action as an increase in blood pressure is a concern when it comes to children conceived through ART.The study appears in the Journal of the American College of Cardiology.
The two companies had invested Rs 50 crore each as equity in the joint venture. NTPC-BHEL Power Projects Pvt Ltd was set up in December 2007 as a large capacity automatic filling machine detailss Factory 50:50 joint venture for manufacturing power equipment. New Delhi: India's biggest power producer NTPC Ltd has decided to exit the joint venture with BHEL, saying it is not a manufacturer of equipment and would rather concentrate on setting up and operating power plants.NTPC-BHEL Power Projects Pvt Ltd was set up in December 2007 as a 50:50 joint venture for manufacturing power equipment.The joint venture's first manufacturing facility at Mannavaram in Chittoor district of Andhra Pradesh started operations in 2016 but had very little orders. Top NTPC sources said the company has decided to exit the venture and has informed the power ministry about its intentions.
NTPC wants BHEL to buy its equity in the joint venture, they said. The two companies had invested Rs 50 crore each as equity in the joint venture. The power producer wants BHEL to acquire its 50 per cent stake in the JV as also all the assets and liabilities and absorb all the employees, they said.The joint venture had little revenue visibility and needed a fresh injection of new orders or a new blueprint to sustain itself. Also, a drying market for thermal power equipment has had a toll on the joint venture company.Fund crunch, land acquisition and environmental issues, general lack of demand for coal-based power and government's emphasis on renewable sources of power have left little to fight for in the thermal power equipment market.Originally, NTPC had lobbied with the government to force Bharat Heavy Electricals Ltd (BHEL) to form a joint venture company.
This because NTPC thought BHEL was slow in supplying equipment, leading to delays in commissioning of its plants. The joint venture was to carry out engineering, procurement and construction activities in the power sector.Its life largely depended on orders from NTPC, managing to secure only four orders in over a decade-long existence – the largest being of Rs 2,219 crore for the 500 MW Feroze Gandhi Unchahar thermal power project out of total orders worth Rs 2,717 crore.Industry sources said the two state-owned companies had come together with the understanding that part of the work of projects that BHEL bagged from NTPC would be given to the joint venture company.The role of the equal joint venture was initially confined to balance of plant equipment such as coal-handling, ash-handling and water treatment facility.
Also find out about the signs and symptoms of infertility in males. Representational Image. (Photo: Pixabay) New Delhi: Infertility, both in men and women, has become quite common these days and is on the rise in India. As per estimates, there has been a 20% to 30% rise in infertility in the country in the last five years.Infertility is neither an urban phenomenon nor is it confined only to women. Studies have shown that in nearly 30% of all infertility cases, the cause can be attributed to a problem in the man.However, in India, male infertility is largely conveyor belts Factory an ignored phenomenon and women are subjected to a lot of social stigma for being unable to bear children. The need of the hour is, therefore, to give equal importance to male infertility and create awareness about the condition.Speaking about this, Dr Hrishikesh D Pai, Director IVF & Infertility at Fortis La Femme Hospital, Delhi & Secretary General of the Federation of Obstetrics and Gynaecological Societies of India said, "Infertility is not just a woman's problem and it is important to raise awareness about male infertility and the causative factors.
Infertility is broadly used to denote a range of conditions, which affect both men and women."He added, "In men, the most common reasons for infertility include alow sperm count and poor motility of the sperm. Other factors such as excessive consumption of foods that increase estrogen in the blood, long-term inhalation of toxins in the air, erectile dysfunction, early ejaculation of semen, cancer or infection of the genital system and diabetes also contribute to the condition. Increasingly, following an unhealthy lifestyle including diet imbalance, addiction to smoking or alcoholism, sedentary existence, or mental and emotional stress, have all become factors that contribute to a poor sperm count."The signs and symptoms of infertility in males may include: problems with sexual function; pain, swelling or a lump in the testicle area; recurrent respiratory infections; decreased facial or body hair or other signs of a chromosomal or hormonal abnormality; having a lower than normal sperm count (fewer than 15 million sperm per milliliter of semen or a total sperm count of less than 39 million per ejaculate).The basic test to determine male infertility is semen analysis. If there are any abnormalities, tests are repeated after a certain duration as advised by the doctor.Dr Nandita Palshetkar, Director, IVF and Infertility at Fortis Bloom IVF Center at La Femme GK 2 and Fortis Hospital Gurgaon & President-elect of the Federation of Obstetrics and Gynaecological Societies of India said, "Although infertility is still considered to be a woman's problem in India, the fact is that in 30% of the infertility cases, the problem is solely with the male partner. It is, therefore, imperative that even the men get tested and at the earliest. Men usually put off testing to avoid embarrassment.""However, getting diagnosed at an early stage will not only save discomfort and expense but also help in timely treatment. The bright side is that recent medical breakthroughs have helped even men with very few sperms to become fathers. It is also important to make certain lifestyle changes such as quitting smoking and drinking, and consuming a healthy diet, all of which can help in preventing infertility and avoiding any possible complications," she added.Some treatment options for addressing male infertility include the following.Intrauterine Insemination (IUI) -
This method can be tried when the sperm count is at least 10 million. In this process, the semen is washed using special methods in a lab and a small quantity of sperms are placed, using a thin tube, inside the woman's womb. This is a simple, inexpensive procedure.Intracytoplasmic Sperm Injection (ICSI) - This is akin to a test-tube baby procedure. Eggs from the women are removed with a needle under sonography control and placed under a microscope. Each sperm is picked up with a needle and injected directly into the egg with a micromanipulator. The eggs then fertilize and divide. After two to three days, the embryo is placed in the womb.PESA, TESA- At times even when a hormone test is normal, there may be no sperms in the semen. In such cases, the sperms can be removed directly from the testes using a tiny needle. These are then injected into the egg using the ICSI procedure.Donor sperms- There are also cases of complete testicular failure with abnormal hormones and no sperms. In such cases, donor sperms obtained from a semen bank. This is then injected into the woman.
Scientists have been searching for an effective brain-protecting stroke therapy for decades. Representational Image. (Photo: Pixabay) Washington: Hibernating ground squirrels have provided clues to new treatments for brain damage caused by stroke.While the animals&automatic liquid soft packaging machines Suppliers39; brains experience dramatically reduced blood flow during hibernation, just like human patients after a certain type of stroke, the squirrels emerge from their extended naps suffering no ill effects.Now, a team of NIH-funded scientists identified a potential drug that could grant the same resilience to the brains of ischemic stroke patients by mimicking the cellular changes that protect the brains of those animals."For decades scientists have been searching for an effective brain-protecting stroke therapy to no avail. If the compound identified in this study successfully reduces tissue death and improves recovery in further experiments, it could lead to new approaches for preserving brain cells after an ischemic stroke," said researcher Francesca Bosetti.Currently, the only way to minimize stroke-induced cell death is to remove the clot as soon as possible.
A treatment to help brain cells survive a stroke-induced lack of oxygen and glucose could dramatically improve patient outcomes, but no such neuroprotective agents for stroke patients exist.Recently, researchers led by John Hallenbeck found that a cellular process called SUMOylation goes into overdrive in a certain species of ground squirrel during hibernation. Hallenbeck suspected this was how the animals' brains survived the reduced blood flow caused by hibernation, and subsequent experiments in cells and mice confirmed his suspicions.SUMOylation occurs when an enzyme attaches a molecular # tag called a Small Ubiquitin-like Modifier (SUMO) to a protein, altering its activity and location in the cell. Other enzymes called SUMO-specific proteases (SENPs) can then detach those tags, thereby decreasing SUMOylation.Lead author Joshua Bernstock and his colleagues examined whether any of over 4,000 molecules from the NCATS small molecule collections could boost SUMOylation by blocking a SENP called SENP2, which would theoretically protect cells from a shortage of life-sustaining substances.The researchers first used an automated process to examine whether the compounds prevented SENP2 from severing the connection between a tiny metal bead and an artificial SUMO protein created in the lab of Wei Yang, Ph.D., the study's other senior author and an associate professor at Duke University in Durham, NC. This system, along with computer modeling and further tests performed both in and outside of cells, whittled the thousands of candidate molecules down to eight that could bind to SENP2 in cells and were non-toxic.
Two of those - ebselen and 6-thioguanine - were then found to both boost SUMOylation in rat cells and keep them alive in the absence of oxygen and glucose.A final experiment showed that ebselen boosted SUMOylation in the brains of healthy mice more than a control injection. 6-thioguanine was not tested because it is a chemotherapy drug with side effects that make it unsuitable as a potential stroke treatment. The researchers now plan to test whether ebselen can protect the brains of animal models of stroke.Because SUMOylation affects a variety of molecules, Bernstock believes his group's approach could inspire similar attempts to treat neurological conditions by targeting pathways with wide-ranging effects. He also hopes it will prompt others to look to natural models, as he and Hallenbeck did with the ground squirrel.The study appears in The FASEB Journal.
The Daiwa waching machine incorporates thermal protectors which are meant to protect the motor from impact resistance. In the shade of Maroon, this semi-automatic washing machine is available in the stores across Punjab, Uttar Pradesh, Haryana and Delhi. Daiwa expands its range of consumer durables with the semi-automatic top load washing machine D65SWM18 with the capacity of 6.5 kg.Daiwa claims the designed of the washing machine is sturdy and it has dynamically durable exterior.
The washing machine comes in the signature design of distinct wash and drain tub along with a transparent, paneled plastic lid for convenience.With a dual roto pulsator, it’s equipped with higher spin speed & lower drying time, as claimed by the company. Moreover, the lint filter captures the lint or any dirt that is released from the clothes while washing. The Daiwa waching machine incorporates thermal protectors which are meant to protect the motor from impact resistance.The company says it is designed to prevent overheating that cause motor China conveyor belts Suppliers failure and possesses rust-proof body with the configuration of high-quality plastic which endures heavily humid climate without getting corroded.In the shade of Maroon, this semi-automatic washing machine is available in the stores across Punjab, Uttar Pradesh, Haryana and Delhi. It is priced at Rs 7,599.
There s a limited pool of talent, and viable candidates who smell the desperation are putting a high price on their skills. From Silicon Valley to Wall Street, there’s increasing demand for highly-skilled workers in Artificial Intelligence and machine learning. But there’s a limited pool of talent, and viable candidates who smell the desperation are putting a high price on their skills. (Photo: Pixabay) From Silicon Valley to China composite film liquid flexible packaging machines Factory Wall Street, there’s increasing demand for highly-skilled workers in Artificial Intelligence and machine learning. But there’s a limited pool of talent, and viable candidates who smell the desperation are putting a high price on their skills.The number of job postings featuring “artificial intelligence” or “machine learning” in their description has doubled since 2015, according to global jobs site Indeed.com.
Prospective employees are increasingly seeking out those jobs, too. Search entries for AI and machine learning positions have increased by 182 percent over the last three years. But more job searches don’t mean more qualified applicants, as industries struggle to find sufficiently skilled candidates.“As AI development and adoption continues to rise across industries, it’s likely there will be more competition for this talent,” said Raj Mukherjee, senior vice president of product at Indeed.“It may be cause for concern for employers looking to find workers with AI skill sets, since these jobs require highly skilled workers with backgrounds in natural language processing, machine learning, and data science.”Indeed said it analysed millions of job postings in the US from June 2015 through June 2018.
The report identified job titles that saw more than 20 per cent of postings list “artificial intelligence” or “machine learning” in the description and derived information about salary and location.If you’re looking to get into AI, set your sights on New York City, according to the report. Surprisingly, New York and not San Francisco boasts the highest percentage of AI and machine learning positions in a single metro area, with more than 11 per cent of national job postings.The technology sector has offered the highest-paying jobs in the US for the last four consecutive years, according to a recent Glassdoor report. Companies such as Apple Inc, Amazon.com Inc, Alphabet Inc, Facebook Inc and Uber Technologies Inc have long paid lucrative salaries to highly technical candidates with machine learning skills.Now other industries, including finance and healthcare, are doling out hefty paychecks as they seek to grab AI talent. Across the board, companies are paying six-figure salaries to attract workers from a limited pool of qualified candidates.A director of analytics received the highest average pay among AI and machine learning jobs this year, topping off at $140,837, the report stated.
Principal scientists, machine learning engineers, computer vision engineers and data scientists China conveyor belts Manufacturers also saw highly competitive salaries, with the lowest average base pay well over USD 130,000.“The industry needs to be creative in order to solve the supply-demand imbalance, one way to do so is by embracing job seekers with non-traditional backgrounds or by training them on the job,” Mukherjee said. “As companies continue to adopt AI solutions or develop their own in-house capabilities, it’s likely that demand by employers for these skills will continue to rise.” - By Bloomberg